The poster consists of 3 panels with multiple frames.

The left hand panel, with 4 frames, is headed: Various frequently encountered rats that transmit plague 幾種常見的傳染鼠疫的老鼠. It depicts three types of common rats that can spread plague, and introduces how they spread plague and the main types of plague (bubonic 腺鼠疫 and pulmonary 肺鼠疫).

The centre panel, with 6 frames, is headed: How to prevent plague from spreading 怎樣防止鼠疫傳染. It includes advice, such as preventing rats getting at garbage and food, crawling into grain hoards, elevating hay stacks, filing holes in walls, and making sure that furniture in the home is not too tight against the wall.

The right hand panel, with 12 panes, is headed: Various methods for catching rats and exterminating fleas 幾種捕捉老鼠和消滅跳蚤的方法.

Left hand slogan reads: Thoroughly defeat American imperialist bacteriological warfare 徹底打敗美帝國主義的細菌戰.

Right hand slogan reads: Everyone participate in the Patriotic Epidemic Prevention Health Campaign 人人都來參加愛國防疫衛生運動.

Publication details: Beijing: Peoples Fine Arts Press, May 1952 (first edition). 中央衛生部宣傳處, 中華全國美術工作者協會編, 北京新國畫研究會集體創作; 人民美術出版社出版，一九五二年五月北京初版.