A series of descriptions of, and observations on, various chemical experiments, fos 1-67, with an index at fos 77v-79r. This is followed by medical recipes written in another hand, fos 68-76 and 84v, the last of which is dated 1706. On fo. 1 in the second hand is 'John Fry / Wooburne / Beddfordshire', and opposite in the same hand 'Hic Liber est meus'. Most of the versos are blank. Loose in the book are accounts on a slip of paper dated 6 April [17]74.