Diaries, notes and reports recording Christy's research for the first Royal Society Sleeping Sickness Commission in Africa. The medical expedition was a response to the spreading Uganda Sleeping Sickness epidemic of 1901. Its aim was to elucidate the role of the Filaria perstans parasite in causing the disease. Christy travelled widely in Uganda, British and German East Africa, and the upper Sudan to map the distributions of the parasite and the disease. His findings were important in disproving the hypothetical causal relationship, and isolating sleeping sickness.

There are also letters from Christy reporting on his prospecting mission for the Uganda & East Africa Exploration Syndicate. It had despatched him to locate forests rich in the rubber producing tree Funtumia elastica, and to apply for concessions to them.